O fabricante fornece Benzocaína CAS 94-09-7 em estoque

Low price Benzocaine CAS 94-09-7 in stock

Low price Benzocaine CAS 94-09-7 in stock

Low price Benzocaine CAS 94-09-7 in stock

Product Information

Product Name: Benzocaine

Synonyms:NSC 4688;Benzocaine (See B197952 for Labelled);Benzocaine, USP, EP;Ethyl 4-aMinobenzoate, 98% 100GR;

Ethyl 4-aMinobenzoate, 98% 500GR;(p-(Ethoxycarbonyl)phenylaMine;4-(Ethoxycarbonyl)phenylaMine;

4-Aminobenzoic Acid Ethyl Ester Benzocaine

CAS:94-09-7

MF:C9H11NO2

MW:165.19

EINECS:202-303-5

Product Categories:C8 to C9;Carbonyl Compounds;Aromatic Esters;Esters;Amines;Aromatics;

Intermediates & Fine Chemicals;Pharmaceutical intermediate;API;Pharma materials;

Intermediate of Tetracaine hydrochloride;medical intermediate;Benzocaine;organic interme;Pharmaceuticals;

Research Chemical;94-09-7

Mol File:94-09-7.mol

Benzocaine Chemical Properties

Melting point 88-90 °C

Boiling point 172 °C (12.7517 mmHg)

density 1.17

refractive index 1.5600 (estimate)

Fp 172°C/13mm

storage temp. 2-8°C

solubility alcohol: soluble1 gm in 5 ml

form Crystalline Powder

pka2.5(at 25℃)

color White

Odorodorless

Water Solubility Soluble in ethanol, chloroform, ethyl ether and dilute acids. Sparingly soluble in water

Merck 14,1086

BRN 638434

Stability:Stable. Combustible. Incompatible with strong oxidizing agents.

InChIKeyBLFLLBZGZJTVJG-UHFFFAOYSA-N

LogP1.860

CAS DataBase Reference94-09-7(CAS DataBase Reference)

NIST Chemistry ReferenceBenzoic acid, 4-amino-, ethyl ester(94-09-7)

EPA Substance Registry SystemBenzocaine (94-09-7)

Description:

Benzocaine (ethyl p-aminobenzoate) is used topically by itself or in combination with menthol or phenol in nonprescription dosage forms such as gels, creams, ointments, lotions, aerosols, and lozenges to relieve pain or irritation caused by such conditions as sunburn, insect bites, toothache, teething, cold sores or canker sores in or around the mouth, and fever blisters. Benzocaine is a lipophilic local anesthetic agent with a short duration of action.

Like most amino ester-type local anesthetics, it is easily hydrolyzed by plasma cholinesterase. Because of its low pKa, however, it is un-ionized under most physiological conditions and, therefore, can only bind to the lipid side of the local anesthetic receptor. It also can easily cross membranes into systemic circulation to cause systemic toxicities. Furthermore, being a PABA derivative, it has similar allergenic properties to procaine and is contraindicated with sulfonamide antibacterial agents.

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